| 发明名称 |
LACTAM INHIBITORS OF CHOLESTEROL ESTERASE |
| 摘要 |
The present invention is related to compounds which inhibit pancreatic cholesterol esterase. The compounds have formula (I), wherein R<1> is H or C1-6 alkyl; R<2> is H or C1-6 alkyl; R<3> is H or C1-6 alkyl; X is CHR<6>, S or O; R<6> is H or C1-6 alkyl; R<4> is a hydrophobic moiety; and pharmaceutically acceptable salts thereof.
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| 申请公布号 |
WO9534566(A1) |
申请公布日期 |
1995.12.21 |
| 申请号 |
WO1995US07450 |
申请日期 |
1995.06.13 |
| 申请人 |
SANOFI WINTHROP, INC. |
发明人 |
RUBIN, BYRON;MATTES, KENNETH, C.;MUNGAL, TERRENCE, C. |
| 分类号 |
C07D499/897;A61K31/43;A61P3/06;A61P43/00;C07D499/00;C07D499/893;(IPC1-7):C07D499/00;A61K31/425 |
主分类号 |
C07D499/897 |
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