发明名称 |
IMMUNIZATION BY INOCULATION OF DNA TRANSCRIPTION UNIT |
摘要 |
This invention relates to a method of immunizing a vertebrate, comprising introducing into the vertebrate a DNA transcription unit which comprises DNA encoding a desired antigen or antigens. The uptake of the DNA transcription unit by a host vertebrate results in the expression of the desired antigen or antigens, thereby eliciting humoral or cell-mediated immune responses or both humoral and cell-mediated responses. The elicited humoral and cell-mediated response can provide protection against invention by pathogenic agents, provide an anti-tumor response, or provide contraception. The host can be any vertebrate, avian or mammal, including humans. |
申请公布号 |
WO9520660(A3) |
申请公布日期 |
1995.12.21 |
申请号 |
WO1995US00997 |
申请日期 |
1995.01.25 |
申请人 |
UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER;ST. JUDE CHILDREN'S RESEARCH HOSPITAL |
发明人 |
ROBINSON, HARRIET, L.;FLYNAN, ELLEN, F.;WEBSTER, ROBERT, G.;LU, SHAN |
分类号 |
C12N15/09;A61K9/16;A61K31/70;A61K35/76;A61K38/00;A61K39/00;A61K39/145;A61K39/15;A61K39/21;A61K48/00;A61P31/12;A61P35/00;A61P37/04;C07H21/04;C07K14/11;C07K14/14;C07K14/155;C07K14/16;C12N15/44;C12N15/46;C12N15/48;C12N15/49;C12N15/88;C12P21/02;C12R1/91 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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