| 发明名称 |
CALCIUM BINDING RECOMBINANT ANTIBODY AGAINST PROTEIN C |
| 摘要 |
A Ca<2+> dependent recombinant antibody that specifically binds to a specific twelve peptide sequence (E D Q V D P R L I D G K) in the activation region of the Protein C has been constructed. The antibody does not bind to Activated Protein C and can be used to inhibit activation of Protein C by thrombin-thrombomodulin, in purification of Protein C, and in treatment of tumors.
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| 申请公布号 |
WO9534652(A1) |
申请公布日期 |
1995.12.21 |
| 申请号 |
WO1995US07372 |
申请日期 |
1995.06.09 |
| 申请人 |
OKLAHOMA MEDICAL RESEARCH FOUNDATION |
发明人 |
REZAIE, ALIREZA;ESMON, CHARLES, T. |
| 分类号 |
C12N15/09;A61K38/00;A61K39/395;A61P35/00;A61P43/00;C07K16/40;C07K16/46;C07K17/00;C12N15/13;C12P21/08;C12R1/91;(IPC1-7):C12N15/13;A61K33/06;A61K38/19 |
主分类号 |
C12N15/09 |
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