发明名称 Treatment of influenza virus infection using antivirals that inhibit acylation/palmitylation of hemagglutinin
摘要 PCT No. PCT/US95/06292 Sec. 371 Date Mar. 6, 1997 Sec. 102(e) Date Mar. 6, 1997 PCT Filed May 17, 1995 PCT Pub. No. WO95/32309 PCT Pub. Date Nov. 30, 1995The present invention relates to assays for the identification of compounds that block palmitylation of influenza virus HA and inhibit virus assembly. In another aspect of the invention, the compounds which inhibit virus assembly, infection and/or replication and which demonstrate a good therapeutic index may be used to treat influenza infection.
申请公布号 AU2595295(A) 申请公布日期 1995.12.18
申请号 AU19950025952 申请日期 1995.05.17
申请人 THE MOUNT SINAI SCHOOL OF MEDICINE OF THE CITY UNIVERSITY OF NE 发明人 PETER PALESE
分类号 A61K31/336;A61K38/00;C07K14/11;C12N7/00;C12N15/09;C12Q1/48;C12Q1/70;G01N33/569;G01N33/92 主分类号 A61K31/336
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