发明名称 |
cDNA FOR HUMAN METHYLENETETRAHYDROFOLATE REDUCTASE |
摘要 |
The present invention relates to a cDNA probe for human methylenetetrahydrofolate reductase (MTHFR), and its uses. The probe of the present invention may be used for the identification of sequence abnormalities in patients with severe or mild MTHFR deficiency, including cardiovascular patients and patients with neurologic symptoms. A human MTHFR protein which hybridizes to the probe of the present invention may be used for therapy of MTHFR-deficiency patients by biochemical or pharmacological approaches.
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申请公布号 |
WO9533054(A1) |
申请公布日期 |
1995.12.07 |
申请号 |
WO1995CA00314 |
申请日期 |
1995.05.25 |
申请人 |
MCGILL UNIVERSITY;ROZEN, RIMA;GOYETTE, PHILIPPE |
发明人 |
ROZEN, RIMA;GOYETTE, PHILIPPE |
分类号 |
A61K38/00;A61K48/00;C12N9/06;C12N15/53;C12Q1/68;(IPC1-7):C12N15/53 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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