FLT-4 (FMS-LIKE TYROSINE-KINASE), FLT-15, VARIANTS THEREOF USES AS GROWTH FACTOR INHIBITORS

摘要

Disclosed is an altered, soluble form of the FLT polypeptide being capable of binding to VEGF and thereby exerting an inhibitory effect thereon, the polypeptide comprising five or fewer complete immunoglobulin-like domains, together with pharmaceutical compositions comprising the polypeptide, and various uses thereof.