| 发明名称 |
COMPOSITIONS AND METHODS FOR CELL TRANSFORMATION |
| 摘要 |
The present invention relates to methods and compositions for the transformation of cells. In particular, compositions and methods are disclosed which include combinations of the nucleic acid of interest and polyhydroxylated or polyglycosylated steroid molecules. Most preferably, exogenous or endogenous nucleic acid is contacted with the cell in the presence of a bile acid (e.g., cholic acid) derivatized with an amine-containing side chain.
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| 申请公布号 |
WO9529186(A1) |
申请公布日期 |
1995.11.02 |
| 申请号 |
WO1995US04806 |
申请日期 |
1995.04.20 |
| 申请人 |
THE TRUSTEES OF PRINCETON UNIVERSITY |
发明人 |
KAHNE, SUZANNE, WALKER;KAHNE, DANIEL, E. |
| 分类号 |
C12N15/09;A61K31/575;A61K47/14;A61K48/00;C07J3/00;C07J5/00;C07J7/00;C07J9/00;C07J17/00;C07J31/00;C07J41/00;C07J43/00;C07J51/00;C12N15/113;C12N15/87;C12P21/02;C12R1/91;(IPC1-7):C07J3/00;A61K31/70;A61K31/705;C07H19/00;C07H21/00;C07H21/02;C07H21/04 |
主分类号 |
C12N15/09 |
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