发明名称 INHIBITION, CONTROL AND REGRESSION OF ANGIOGENESIS
摘要 The use of: (a) a non-steroidal anti-inflammatory agent, and (b) hyaluronic acid and/or salts thereof and/or homologues, analogues, derivatives, complexes, esters, fragments, and subunits of hyaluronic acid, in the manufacture of a pharmaceutical composition for inhibiting, controlling and/or regressing angiogenesis in a therapy wherein dosage amounts taken from the composition each comprise: (1) a therapeutically effective amount of component (a); and (2) a therapeutically effective amount of the hyaluronic acid and/or salts thereof and/or homologues, analogues, derivatives, complexes, esters, fragments, and sub-units of hyaluronic acid, the pharmaceutical composition being characterized in that for each dosage amount taken from the pharmaceutical composition, the amount of components (a) and (b) inhibit, control and/or regress angiogenesis.
申请公布号 CA2121454(A1) 申请公布日期 1995.10.16
申请号 CA19942121454 申请日期 1994.04.15
申请人 NORPHARMCO INC. 发明人 WILLOUGHBY, DEREK A.;ALAM, CHANDAN;ASCULAI, SAMUEL S.;FALK, RUDOLF E.;HARPER, DAVID W.
分类号 A61K47/36;(IPC1-7):A61K31/725 主分类号 A61K47/36
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