发明名称 New Polyiodinated compounds their preparation and their use as contrast media for radiology
摘要 PCT No. PCT/FR94/00305 Sec. 371 Date Nov. 1, 1994 Sec. 102(e) Date Nov. 1, 1994 PCT Filed Mar. 21, 1994 PCT Pub. No. WO94/21600 PCT Pub. Date Sep. 29, 1994The present invention relates to polyiodinated compounds with a single molecular weight having a molecular concentration of iodine of greater than approximately 20% by weight, and in particular greater than approximately 30% by weight, containing at least 9 iodine atoms and having a molecular weight above 2000 and below approximately 50,000, and in particular above 2000 and below approximately 20,000, said compounds possessing either a zero overall electrical charge or at least two anionic charges, and persisting in the vascular compartment at a value equal to at least approximately 30% by weight of the injected dose in a subject five minutes after intravascular administration in the said subject.
申请公布号 ZA9401959(B) 申请公布日期 1995.09.21
申请号 ZA19940001959 申请日期 1994.03.21
申请人 GUERBET S. A. 发明人 DOMINIQUE MEYER;SOIZIC LE GRENEUR;GAEL LE LEM;CHRISTIAN SIMONOT;CATHERINE CHAMBON
分类号 A61K49/04;C07C237/46 主分类号 A61K49/04
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