发明名称 |
Inhibitors of cell-mediated disorders |
摘要 |
The present invention provides a method for blocking a cellular proton pump that comprises contacting a cell with a cellular proton pump-blocking effective quantity of In-EDTA or Tl-EDTA. The present invention also provides a method of treating or preventing cell-mediated disorders in a vertebrate animal by administering In-EDTA or Tl-EDTA to the vertebrate animal, as well as a method for stopping the cellular proton pump-blocking effect of Group IIIa metals such as Ga, In, and Tl, through use of suitable chelating agents. Suitable compositions for use in the aforementioned methods are provided as well. |
申请公布号 |
AU2060295(A) |
申请公布日期 |
1995.08.29 |
申请号 |
AU19950020602 |
申请日期 |
1995.02.06 |
申请人 |
THE JEWISH HOSPITAL OF ST. LOUIS |
发明人 |
STEVEN L TEITELBAUM;HARRY C BLAIR;PAUL H SCHLESINGER |
分类号 |
A61K31/198;A61K31/28;A61L24/02;A61L27/02 |
主分类号 |
A61K31/198 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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