| 摘要 |
The present invention discloses compounds of the formula <IMAGE> or a pharmaceutically-acceptable addition salt thereof wherein R' and R'' independently of each other are hydrogen or alkyl, or R' and R'' together form a 3 to 6 membered alkylene chain; one of R1 and R2 is aryl which may be substituted one or more times with halogen, CF3, CN, OH, alkyl, cycloalkylalkyl, alkenyl, alkynyl, alkoxy, amino, nitro, sulphamoyl, tetrazolyl, CO2H, CO2-alkyl and the other of R1 and R2 is hydrogen, halogen, alkoxy, amino or alkyl; and R4, R5, R6 and R7 independently of each other are hydrogen, halogen, amino, nitro, CN, OH, CF3, alkyl or alkoxy; and n is 0 or 1; provided that neither of R1 and R2 is phenyl or substituted phenyl when n is 0. The compounds are useful as pharmaceuticals, for example, in the treatment of ischemia, anoxia, migraine and psychosis.
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