Halogenated Derivatives of 2,3'-O-Cyclocytidine Compounds and Process for Production Thereof

摘要

A 5'-halo-2,3'-O-cyclocytidine of Formula I: I wherein: X is a bromide, chloride, or iodide; Y is halide, sulfate, acetate, tosyl, mesyl, benzoate, and phosphate; R1 is hydrogen; and R2 is a hydroxy protecting group. Pharmaceutical compositions containing the above compounds exhibit antineoplastic activity.