发明名称 |
DIAGNOSIS OF METASTATIC CANCER BY THE MTS-1 GENE |
摘要 |
The present invention is directed towards the diagnosis of malignant cancer by detection of the <u>mts-1</u> mRNA or the <u>mts-1</u> protein, encoded by the <u>mts-1</u> gene. The present invention contemplates the use of recombinant <u>mts-1</u> DNA and antibodies directed against the <u>mts-1</u> protein to diagnose the metastatic potential of several types of tumor cells, including, for example, thyroid, epithelial, lung, liver and kidney tumor cells. The present invention is also directed to mammalian cell lines and tumors with high and low metastatic potential which have been developed to serve as useful model systems for <u>in</u> <u>vitro</u> and <u>in</u> <u>vivo</u> anti-metastasis drug screening.
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申请公布号 |
WO9520656(A1) |
申请公布日期 |
1995.08.03 |
申请号 |
WO1995US01214 |
申请日期 |
1995.01.31 |
申请人 |
RESEARCH CORPORATION TECHNOLOGIES, INC. |
发明人 |
ZAIN, SAYEEDA;LUKANIDIN, EUGENE |
分类号 |
G01N33/574;A61K38/00;A61K39/395;A61K48/00;A61P35/00;C07H21/04;C07K14/47;C07K16/18;C12N1/21;C12N5/00;C12N5/10;C12N15/09;C12N15/12;C12R1/19;C12R1/91;(IPC1-7):C12N15/12;C12N15/63;C12N1/19 |
主分类号 |
G01N33/574 |
代理机构 |
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主权项 |
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地址 |
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