WATERSOLUBLE AZOLE ANTIFUNGALS

摘要

A compound of formula (I), an acid or base addition salt thereof or a stereochemically isomeric form thereof, wherein A and B taken together form -N=CH-, -CH=N-, -CH2-CH2, CH=CH-, -C(=O)-CH2-, -CH2-C(=O); D is a radical of formula (D1), (D2), (D3); L is a radical of formula (L1), (L2); Alk is a C1-4alkanediyl radical; R<1> is halo; R<2> is hydrogen or halo; R<3> is hydrogen, C1-6alkyl, phenyl or halophenyl; R<4> is hydrogen, C1-6alkyl, phenyl or halophenyl; R<5> is hydrogen or C1-6alkyl; R<6> is hydrogen, C1-6alkyl, C1-6alkyloxycarbonyl, or R<5> and R<6> taken together with the nitrogen atom to which they are attached form a heterocyclic ring. Active intermediates, compositions and methods of preparing compounds, compositions are described.