发明名称 BRAIN FUNCTION IMPROVER
摘要 PURPOSE:To obtain a brain function improver containing a sinapic acid derivative as an active ingredient and used for improving and treating cerebral infarction or dementia. CONSTITUTION:This brain function improver contains a sinapic acid derivative of formula I [R1 and R2 each is H or a lower alkyl; R2 is OH, methoxy or methoxymethylenoxy; R4 is COR5 (R5 is OH, a lower alkoxy, an amine which may be substituted by an aromatic alkoxy, or methoxymethylenoxy) or formula II (R6 is a lower alkyl)] and its physiologically permissible salt as an active ingredient. The compound is used as an oral agent or a parenteral agent. In order to exhibit expected effect, in the oral preparation, 5-5000mg of the compound is preferably administrated in several portions per day and in the parenteral preparation, 0.5-100mg of the compound is preferably subjected to intravenous injection, perfusion injection, subcutaneous injection or intramuscular injection.
申请公布号 JPH07179338(A) 申请公布日期 1995.07.18
申请号 JP19930346123 申请日期 1993.12.22
申请人 TSUMURA & CO 发明人 IIZUKA SUSUMU;ISHIGE ATSUSHI;YAMAGUCHI TAKUJI;IKETANI YUKINOBU
分类号 C07D295/18;A61K31/16;A61K31/165;A61K31/215;A61K31/495;A61P25/28 主分类号 C07D295/18
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