摘要 |
PCT No. PCT/US91/05018 Sec. 371 Date Mar. 12, 1993 Sec. 102(e) Date Mar. 12, 1993 PCT Filed Jul. 22, 1991 PCT Pub. No. WO92/05775 PCT Pub. Date Apr. 16, 1992.A device for the controlled delivery of an insoluble or partially aqueous insoluble beneficial agent to an aqueous containing environment. The device comprises a shaped wall that surrounds and defines an internal reservoir. The wall is formed at least in part of a sintered polymer microporous membrane permeable to a beneficial agent-containing hydrophobic medium when the wall is present in the aqueous containing environment. The reservoir contains a mixture of a hydrophilic swellable composition and a beneficial agent-containing hydrophobic medium.
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