发明名称 |
STABILE HÄMOGLOBINREFERENZLÖSUNG. |
摘要 |
A stable reference solution for calibrating and monitoring blood gas instrumentation is disclosed. The solution comprises an aqueous mixture containing a hemoglobin solution derived from a mammalian source which comprises at least about 95% reduced hemoglobin. The solution additionally contains a bicarbonate buffer and a metal catalyzed methemoglobin reducing system and an organic buffer. To provide a control element having a variety of properties similar to fresh, whole, human blood, the reference solution is stored in a sealed ampule under an inert atmosphere containing CO2 until just prior to use. The ampule is subsequently opened and the solution is equilibrated with a gas mixture having components which provide gasses in a physiological range to the solution. The solution is characterized by exhibiting properties similar to fresh blood subsequent to equilibration and an extended storage life prior to equilibration. |
申请公布号 |
DE69016415(T2) |
申请公布日期 |
1995.06.08 |
申请号 |
DE1990616415T |
申请日期 |
1990.03.16 |
申请人 |
BIONOSTICS, INC., ACTON, MASS., US |
发明人 |
CHIANG, CHING, ACTON, MA 01720, US |
分类号 |
G01N33/49;G01N27/416;G01N33/50;G01N33/72;G01N33/96;(IPC1-7):G01N33/72 |
主分类号 |
G01N33/49 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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