METHOD FOR FABRICATING MICROPARTICLES IN EMULSION BY MODIFICATION OF THE CHEMICAL COMPOSITION OF THE DISPERSED PHASE AFTER EMULSIFICATION.

摘要

PCT No. PCT/FR93/00791 Sec. 371 Date Feb. 21, 1995 Sec. 102(e) Date Feb. 21, 1995 PCT Filed Aug. 4, 1993 PCT Pub. No. WO94/04260 PCT Pub. Date Mar. 3, 1994The method for producing microparticles is characterized in that it comprises the following steps: preparation of an emulsion of a solution of a substance or a mixture of substances in a dispersing liquid wherein said substance or said mixture are substantially insoluble; incorporating to said dispersed phase a chemical agent substantially insoluble in the dispersing liquid so as to cause within the dispersed phase a chemical or physicochemical reaction responsible for the formation of microparticles which are then isolated.