摘要 |
1,176,157. Orotic acid salt. H. A. NIEPER. 1 Nov., 1968 [15 Nov., 1967], No. 52034/67. Heading C2C. Novel calcium di-orotate (I) is prepared by treating an aqueous solution of orotic acid with a soluble calcium salt in an aqueous solution in stoichiometric amount. Pharmaceutical compositions comprise the novel salt together with a suitable excipient for enteral, parenteral or topical application and are active in the treatment of over weight, inflammatory diseases, arteriosclerosis, atherosclerosis, auto-immune diseases, and osteoporotic decalcification.
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