Heterobiarly derivatives and pharmaceutical compositions thereof

摘要

Heterobiaryl derivatives of the formula R1NH-X1-X2-X3-Y1-Y2-Y3-Y4-E(I) wherein R1, X1 to X3 and Y1 to Y4 are as defined herein, the tautomers, stereoisomers and mixtures thereof, and the salts, particularly the physiologically acceptable salts, thereof with organic or inorganic acids or bases. The derivatives have valuable pharmacological properties, such as inhibiting cell-cell aggregation and cell-matrix interactions.