| 发明名称 |
Use of nitric oxide releasing compounds as protective agents in ischemia reperfusion injury |
| 摘要 |
The present invention provides a method for treating oxygen free radical induced tissue damage associated with ischemia reperfusion injury, wherein nitric oxide is delivered to target cells/tissues through the administration of a nitric oxide-containing compound that spontaneously releases nitric oxide under physiological conditions without requiring the presence of oxygen. |
| 申请公布号 |
AU8130094(A) |
申请公布日期 |
1995.05.23 |
| 申请号 |
AU19940081300 |
申请日期 |
1994.10.31 |
| 申请人 |
THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEP;BOARD OF SUPERVISORS OF LOUISIANA STATE, THE |
发明人 |
DAVID A. WINK JR.;JAMES B MITCHELL;ANGELO RUSSO;MURALI C KRISHNA;INGEBORG HANBAUER;MATTHEW B GRISHAM;DANIEL NEIL GRANGER |
| 分类号 |
C07D295/22;A61K31/10;A61K31/13;A61K31/135;A61K31/14;A61K31/15;A61K31/16;A61K31/195;A61K31/198;A61K31/215;A61K31/44;A61K31/4402;A61K31/4406;A61K31/4409;A61K31/4418;A61K31/445;A61K31/4468;A61K31/495;A61K31/496;A61K38/00;A61K45/00;A61P1/00;A61P1/04;A61P3/08;A61P7/00;A61P9/00;A61P9/08;A61P9/10;A61P9/12;A61P11/00;A61P25/28;A61P29/00;A61P35/00;A61P37/06;A61P43/00;C07D211/98;C07D213/42;C07D271/06 |
主分类号 |
C07D295/22 |
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