发明名称 |
NUCLEIC ACIDS ENCODING MEROSIN, MEROSIN FRAGMENTS AND USES THEREOF |
摘要 |
This invention provides an isolated nucleic acid molecule encoding a subunit of a protein, the protein having an apparent molecular weight of about 800 kD, designated merosin. Also provided are isolated nucleic acid molecules which encode merosin fragments. Anti-merosin antibodies, vectors for the recombinant production of merosin, and the expression of recombinant proteins by use of a host vector system also are provided. The invention further provides the use of merosin to promote neurite growth and for certain diagnostic applications. |
申请公布号 |
WO9508628(A3) |
申请公布日期 |
1995.05.11 |
申请号 |
WO1994US10730 |
申请日期 |
1994.09.21 |
申请人 |
LA JOLLA CANCER RESEARCH FOUNDATION |
发明人 |
ENGVALL, EVA;LEIVO, ILMO |
分类号 |
G01N33/53;A61K38/00;C07K14/78;C07K16/00;C07K16/18;C12N1/21;C12N15/09;C12N15/12;C12P21/08;C12Q1/68;G01N33/574;G01N33/577;G01N33/68 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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