发明名称 |
Vitamin D3 analogues |
摘要 |
A vitamin D3 analogue which includes a hydroxyalkyl substituent in the 1-position and a modified D-ring side chain is described. This novel compound is a potent anti-proliferative substance with activity comparable to that of calcitriol but with a vitamin D3 receptor binding rating of approximately 10-3 compared to that of calcitriol.
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申请公布号 |
US5403832(A) |
申请公布日期 |
1995.04.04 |
申请号 |
US19940284209 |
申请日期 |
1994.08.02 |
申请人 |
THE JOHNS HOPKINS UNIVERSITY |
发明人 |
POSNER, GARY H.;WHITE, MARIA-CHRISTINA |
分类号 |
C07C401/00;C07F9/53;(IPC1-7):C07C401/00 |
主分类号 |
C07C401/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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