This invention provides an isolated, vertebrate nucleic acid molecule encoding the normal protein that prevents development of Wilson's disease. This invention also provides a nucleic acid molecule comprising a nucleic acid molecule of at least 15 nucleotides capable of specifically hybridizing with a sequence included within the sequence of the above-described nucleic acid molecule. Finally, this invention provides various uses of the isolated Wilson's disease gene.
申请公布号
WO9506714(A1)
申请公布日期
1995.03.09
申请号
WO1994US09851
申请日期
1994.09.01
申请人
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF;GENERAL HOSPITAL CORPORATION;GILLIAM, T., CONRAD;TANZI, RUDOLPH, E.