| 摘要 |
Compounds of the structure <IMAGE> I R and R1 are each, independently, hydrogen, or <IMAGE> R2 and R3 are each, independently, alkyl, arylalkyl, or may be taken together to form a cycloalkyl ring; R4 and R5 are each, independently, hydrogen, alkyl, arylalkyl, or may be taken together to form a saturated heterocycle wherein the heterocyclic ring may be optionally mono-, di-, or tri-substituted; m=0-1; and n=0-6; with the proviso that R and R1 are not both hydrogen, or a pharmaceutically acceptable salt thereof, and <IMAGE> II R1 is <IMAGE> R2 and R3 are each, independently, hydrogen, alkyl, arylalkyl, or may be taken together to form a cycloalkyl ring; R4 and R5 are each, independently, hydrogen, alkyl, arylalkyl, or may be taken together to form a saturated heterocycle wherein the heterocyclic ring may be optionally mono-, di-, or tri-substituted; m=0-1; and n=0-6; or a pharmaceutically acceptable salt thereof which are useful as immunosuppressive, antiinflammatory, antifungal, antiproliferative, and antitumor agents.
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