摘要 |
<p>A chroma compound represented by general formula (I), the use thereof as a coronary vasodilator, and intermediates thereof including 4-oxochroman, 4-hydroxychroman, chromene and 3,4-epoxychroman compounds wherein R1 represents cyano, nitro or halogen; R2 represents lower alkoxyalkyl, lower alkoxycarbonyl, hydroxyalkyl, aryloxyalkyl or t-butyldimethylsilyloxyalkyl; R3 represents H, lower alkyl, etc.; R4 represents H, OH, etc.; R5 represents H, etc.; A represents (a); R6 represents substituted aryl, heteroaryl, arylamino, aryloxy or lower alkyl; X represents N-CN, O or S; and R7 represents H or lower alkyl.</p> |