发明名称 3,3-diphenylpropylamines and pharmaceutical compositions thereof
摘要 <IMAGE> (I) Novel 3,3-diphenylpropylamines of formula (I) wherein R1 signifies hydrogen or methyl, R2, R3 and R4 independently signify hydrogen, methyl, methoxy, hydroxy, carbamoyl, sulphanoyl or halogen, and X represents a tertiary amino group -NR5, R6, wherein R5 and R6 signify non-aromatic hydrocarbyl groups, which may be the same or different and which together contain at least three carbon atoms, and which may form a ring together with the amine nitrogen, their salts with physiologically acceptable acids and, when the compounds can be in the form of optical isomers, the racemic mixture and the individual enantiomers, their use as drugs, especially as anticholinergic agents, their use for preparing an anticholinergic drug, pharmaceutical compositions containing the novel amines, and methods for preparing the same.
申请公布号 US5382600(A) 申请公布日期 1995.01.17
申请号 US19910810185 申请日期 1991.12.19
申请人 PHARMACIA AKTIEBOLAG 发明人 JOENSSON, NILS A.;SPARF, BENGT A.;MIKIVER, LEMBIT;MOSES, PINCHAS;NILVEBRANT, LISBET;GLAS, GUNILLA
分类号 C07C43/23;C07C215/54;C07C217/62;C07C309/73;C07D207/08;C07D211/14;C07D211/46;(IPC1-7):A61K31/135;A61K31/165;A61K31/18 主分类号 C07C43/23
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