ANSAMYCIN DERIVATIVES AS ANTIONCOGENE AND ANTICANCER AGENTS

摘要

A compound of formula (I) and pharmaceutically acceptable salts and prodrugs thereof wherein R1, R2, R3, R4, R5 and R6 are as defined below, methods and intermediates useful in the preparation thereof, pharmaceutical compositions thereof and methods of treatment therewith. The compounds of formula (I) are useful in inhibiting oncogene products and as antitumor and anticancer agents.