发明名称 |
N-TERMINAL VDAC VARIANTS AND USES THEREOF |
摘要 |
The present invention relates generally to variants and peptides of the mitochondrial protein, voltage-dependent anion channel (VDAC) and to polynucleotides encoding same. In particular, the present invention is directed to N-terminal truncated and mutated VDAC and specific amino acid and polynucleotide sequences thereof useful in inhibiting apoptosis, and to pharmaceutical compositions comprising same useful in the treatment of diseases associated with excess apoptosis. |
申请公布号 |
WO2007113837(A3) |
申请公布日期 |
2008.02.28 |
申请号 |
WO2007IL00455 |
申请日期 |
2007.04.10 |
申请人 |
BEN-GURION UNIVERSITY OF THE NEGEV;SHOSHAN-BARMATZ, VARDA;CALO, DORON |
发明人 |
SHOSHAN-BARMATZ, VARDA;CALO, DORON |
分类号 |
C07K14/47;A61K38/16;C12N15/12;C12N15/63 |
主分类号 |
C07K14/47 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|