| 摘要 |
<p>A method for removing bile salts from a patient by ion exchange by administering to the patient a therapeutically effective amount of one or more highly crosslinked polymers characterized by a repeat unit having formula (1) or copolymer thereof, where n is an integer; R1 is H or a C¿1?-C8 alkyl group; M is -C-Z-R?2? or -Z-R?2¿; Z is O, NR3, S, or (CH¿2?)m; m = 0-10; R?3¿ is H or a C¿1?-C8 alkyl group; and R?2¿ is (a) or (b) where p = 0-10, and each R?4, R5, R6¿, independently, is H, a C¿1?-C8 alkyl group, or an aryl group, the polymers being non-toxic and stable once ingested.</p> |
