Process for the preparation of 5H-dibenz[b,f]azepine-5-carboxamide

摘要

The invention relates to a simple process for the preparation of 5H-dibenz[b,f]azepine-5-carboxamide (carbamazepine). It can be prepared advantageously by reaction of iminostilbene with alkali metal cyanates in acetic acid, acetic acid-water or acetic acid-alcohol mixtures. Carbamazepine is used for the treatment of a large number of disorders of the central nervous system.