发明名称 USE OF PLATELET-DERIVED GROWTH FACTOR TO IMPROVE COLLATERAL CIRCULATION
摘要 <p>The present invention provides a noninvasive method for improving collateral circulation to tissue at risk of ischemia or ischemic necrosis. Improved collateral circulation is obtained by applying a growth factor from the PDGF family to the area at or around an occluded blood vessel causing compromised direct circulation to the affected tissue. The present invention further provides a method for anastomosing one or more divided blood vessels using a growth factor from the PDGF family. Preferably, the growth factor is administered locally to the end(s) of the divided blood vessel(s) at or around the area where a single divided blood vessel is attached to tissue of an organ at risk of ischemia.</p>
申请公布号 WO1994025056(A2) 申请公布日期 1994.11.10
申请号 US1994004762 申请日期 1994.04.29
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