摘要 |
The present invention provides new antiviral compounds, i.e., michellamines and derivatives and pharmacologically acceptable salts thereof, methods for isolating such antiviral compounds from a plant species of the genus Ancistrocladus, antiviral compositions containing such antiviral compounds, and methods of using such antiviral compounds for treating patients with viral infections. The antiviral compounds of the present invention inhibit the reproduction and cytopathicity of human acquired immunodeficiency viruses. |
申请人 |
THE UNITED STATES OF AMERICA, REPRESENTED BY THE S |
发明人 |
BOYD, MICHAEL, R.;CARDELLINA, JOHN, H., II;MANFREDI, KIRK, R.;BLUNT, JOHN, W.;PANNELL, LEWIS, K.;MCMAHON, JAMES, B.;GULAKOWSKI, ROBERT, J.;CRAGG, GORDON, M.;BRINGMANN, GERHARD;THOMAS, DUNCAN;JATO, JOHNSON |