发明名称 Process for the preparation of 1 beta -ethyl-1 alpha -(hydroxymethyl)-1,2,3,4,6,7,12,12B alpha -octahydro-indolo[2,3,-A]quinolizine and novel intermediates
摘要 PCT No. PCT/HU91/00046 Sec. 371 Date Jun. 25, 1992 Sec. 102(e) Date Jun. 25, 1992 PCT Filed Oct. 30, 1991 PCT Pub. No. WO92/07851 PCT Pub. Date May 14, 1992.The invention relates to a novel process for the preparation of (-) -1 beta -ethyl-1 alpha -(hydroxymethyl) - 1,2,3,4,6,7,12,12b alpha -octahydro-indolo[2,3-a]quinolizine of the formula (I) <IMAGE> (I) and to novel intermediates obtained in this process. The compound of the formula (I) prepared by the process of the invention possesses a peripheral vasodilator effect.
申请公布号 US5352790(A) 申请公布日期 1994.10.04
申请号 US19920877172 申请日期 1992.06.25
申请人 RICHTER GEDEON VEGEYSZETI GYAR RT. 发明人 KREIDL, JANOS;CZIBULA, LASZLO;VISKY, GYOERGY;NEE KIRJAK, MARIA F.;NEE JUHASZ, IDA D.;BRILL, DECEASED, JUDIT;NOGRADI, KATALIN
分类号 A61K31/435;C07D471/14;(IPC1-7):C07D459/00 主分类号 A61K31/435
代理机构 代理人
主权项
地址