发明名称 |
Process for the preparation of 1 beta -ethyl-1 alpha -(hydroxymethyl)-1,2,3,4,6,7,12,12B alpha -octahydro-indolo[2,3,-A]quinolizine and novel intermediates |
摘要 |
PCT No. PCT/HU91/00046 Sec. 371 Date Jun. 25, 1992 Sec. 102(e) Date Jun. 25, 1992 PCT Filed Oct. 30, 1991 PCT Pub. No. WO92/07851 PCT Pub. Date May 14, 1992.The invention relates to a novel process for the preparation of (-) -1 beta -ethyl-1 alpha -(hydroxymethyl) - 1,2,3,4,6,7,12,12b alpha -octahydro-indolo[2,3-a]quinolizine of the formula (I) <IMAGE> (I) and to novel intermediates obtained in this process. The compound of the formula (I) prepared by the process of the invention possesses a peripheral vasodilator effect.
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申请公布号 |
US5352790(A) |
申请公布日期 |
1994.10.04 |
申请号 |
US19920877172 |
申请日期 |
1992.06.25 |
申请人 |
RICHTER GEDEON VEGEYSZETI GYAR RT. |
发明人 |
KREIDL, JANOS;CZIBULA, LASZLO;VISKY, GYOERGY;NEE KIRJAK, MARIA F.;NEE JUHASZ, IDA D.;BRILL, DECEASED, JUDIT;NOGRADI, KATALIN |
分类号 |
A61K31/435;C07D471/14;(IPC1-7):C07D459/00 |
主分类号 |
A61K31/435 |
代理机构 |
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地址 |
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