| 摘要 |
PCT No. PCT/EP94/00438 Sec. 371 Date Aug. 21, 1995 Sec. 102(e) Date Aug. 21, 1995 PCT Filed Feb. 15, 1994 PCT Pub. No. WO94/19320 PCT Pub. Date Sep. 1, 1994 <IMAGE> (I) <IMAGE> (a) <IMAGE> (b) The present invention relates to compounds of formula (I) and salts and prodrugs thereof, wherein Q1 represents a phenyl group substituted by one or more halo optionally substituted naphthyl, optionally substituted indolyl, optionally substituted benzthiophenyl, optionally substituted benzofuranyl, optionally substituted benzyl or optionally substituted fluorenyl; R1 represents H or C1-6alkyl; R2 represents H, C1-6alkyl or C2-6alkenyl; Z1 represents a group selected from (a) or (b). The compounds are tachykinin antagonists useful for treating pain or inflammation, migraine or emesis. |
