发明名称 Pharmaceutical composition containing a stable modification of torasemide
摘要 The present invention provides a process for the preparation of cystalline torasemide in the pure modification I (monoclinic, space group P21/c, melting point 162 DEG C.) from torasemide of modification II (monoclinic, space group P2/n, melting point 169 DEG C.), wherein a suspension of torasemide of modification II is stirred in water with the addition of a catalytic amount of modification I until the rearrangement is complete. The present invention also provides pharmaceutical compositions containing torasemide of modification I.
申请公布号 USRE34672(E) 申请公布日期 1994.07.26
申请号 US19930043631 申请日期 1993.04.08
申请人 BOEHRINGER MANNHEIM GMBH 发明人 TOPFMEIER, FRITZ;LETTENBAUER, GUSTAV
分类号 A61K31/44;A61P7/10;C07D213/74;(IPC1-7):C07D213/74;C07D213/75 主分类号 A61K31/44
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