| 摘要 |
<p>An isolated NF-ATp protein, a T lymphocyte DNA binding protein, is described. Isolated nucleic acids encoding the protein are also disclosed, as are methods for producing the protein by recombinant means. Methods for screening potential immunosuppressant compounds, which interfere with or inhibit lymphokine gene activation through the NF-AT pathway, are described. Such methods detect phosphorylation of the NF-AT protein.</p> |
