摘要 |
Compounds having the structure <IMAGE> wherein (Z-COO is the residue of an iodinated aromatic acid; R is alkyl, cycloalkyl, aryl, aralkyl, <IMAGE> or alkenyl; R1 is H, alkyl, cycloalkyl, aryl, aralkyl, or -CH2-mCO2R3; R2 is H, alkyl, cycloalkyl, aryl, aralkyl, -CH2-nCO2R4, or a <IMAGE> group, wherein Z, R and R1 are as defined above; or R1 and R2, taken together with the carbon atom to which they are attached represent cycloalkyl; R3 is H, alkyl, cycloalkyl, aryl or aralkyl; R4 is H, alkyl, cycloalkyl, aryl or aralkyl; and m, n and p are independently an integer of from 0 to 17; provided that R1 and R2 can not both be H; are useful in the preparation of x-ray contrast compositions for medical imaging.
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