发明名称 Iodinated benzoyl acetals and ketals for x-ray imaging
摘要 Compounds having the structure <IMAGE> wherein (Z-COO is the residue of an iodinated aromatic acid; R is alkyl, cycloalkyl, aryl, aralkyl, <IMAGE> or alkenyl; R1 is H, alkyl, cycloalkyl, aryl, aralkyl, or -CH2-mCO2R3; R2 is H, alkyl, cycloalkyl, aryl, aralkyl, -CH2-nCO2R4, or a <IMAGE> group, wherein Z, R and R1 are as defined above; or R1 and R2, taken together with the carbon atom to which they are attached represent cycloalkyl; R3 is H, alkyl, cycloalkyl, aryl or aralkyl; R4 is H, alkyl, cycloalkyl, aryl or aralkyl; and m, n and p are independently an integer of from 0 to 17; provided that R1 and R2 can not both be H; are useful in the preparation of x-ray contrast compositions for medical imaging.
申请公布号 US5330739(A) 申请公布日期 1994.07.19
申请号 US19920985415 申请日期 1992.12.04
申请人 STERLING WINTHROP INC. 发明人 ILLIG, CARL R.
分类号 A61K49/04;C07C43/303;C07C43/305;C07C43/307;C07C43/313;C07C233/54;(IPC1-7):A61K49/04;C07C69/76;C07C205/00;C07C229/00 主分类号 A61K49/04
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