发明名称 |
BIOCIDAL CHITIN BINDING PROTEINS |
摘要 |
<p>Biocidal proteins capable of isolation from seeds have been characterised. The proteins have an amino acid sequence containing the common cysteine/glycine domain of Chitin-binding Plant Proteins but show substantially better activity against pathogenic fungi, a higher ratio of basic amino acids to acidic amino acids, and/or antifungal activity which results in increased hyphal branching. Antimicrobial proteins isolated from Capsicum, Briza and related species are provided. The proteins show a wide range of antifungal activity and are active against Gram-positive bacteria. DNA encoding the proteins may be isolated and incorporated into vectors. Plants may be transformed with this DNA. The proteins find agricultural or pharmaceutical application as antifungal or antibacterial agents. Transgenic plants expressing the protein will show increased disease resistance.</p> |
申请公布号 |
CA2147122(A1) |
申请公布日期 |
1994.05.26 |
申请号 |
CA19932147122 |
申请日期 |
1993.10.22 |
申请人 |
ZENECA LIMITED |
发明人 |
BROEKAERT, WILLEM FRANS;CAMMUE, BRUNO PHILLIPE ANGELO;OSBORN, RUPERT WILLIAM;REES, SARAH BRONWEN |
分类号 |
A01H5/00;A01N37/46;A01N63/00;A01N65/20;A01N65/32;A01N65/38;A01N65/44;A01P1/00;A01P3/00;C07K14/415;C12N5/10;C12N15/09;C12N15/29;C12N15/82;C12P21/02;C12R1/91;(IPC1-7):C12N15/29;A01N65/00;A61K38/16;A01N37/18;A01N43/50 |
主分类号 |
A01H5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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