摘要 |
PURPOSE:To efficiently produce a 3-hydroxybutyric acid and its ester, useful as medicines such as antibiotic substances or biodegradable polymers and having optical activity. CONSTITUTION:The objective 3-hydroxybutyric acid at a ratio [(R)/(S)] different from that of a raw material mixture is obtained by using a mixture of an (R)-3-hydroxybutyric acid ester with an (S)-3-hydroxybutyric acid ester and reacting a hydrolase therewith. Furthermore, the objective 3-hydroxybutyric acid ester at a ratio [(R)/(S)] different from that of the raw material mixture is obtained. |