发明名称 |
3-INDOLEPYRUVIC ACID DERIVATIVES AND PHARMACEUTICAL USE THEREOF |
摘要 |
3-indolepyruvic acid and derivatives thereof in the form of salts, esters and amides are compounds pharmaceutically active as agents for antagonising disturbances of the central nervous system, such as epilepsy, cerebral ischemia, ictus and Alzheimer's disease, through a mechanism of action which raises the level of kynurenic acid in the brain.
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申请公布号 |
CA1328658(C) |
申请公布日期 |
1994.04.19 |
申请号 |
CA19880567675 |
申请日期 |
1988.05.25 |
申请人 |
POLIFARMA S.P.A. |
发明人 |
POLITI, VINCENZO;DE LUCA, GIOVANNA;DI STAZIO, GIOVANNI;MARGONELLI, ANDREA;MATERAZZI, MARIO |
分类号 |
A61K31/403;A61K31/404;A61K31/405;A61P9/00;A61P25/00;A61P25/08;A61P25/28;C07D209/00;C07D209/14;C07D209/18;(IPC1-7):C07D209/18;C07D403/06 |
主分类号 |
A61K31/403 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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