发明名称 New analgesic and nootropic drugs
摘要 Compounds of general formula: <IMAGE> where: Ar=phenyl or beta-naphtyl, or aromatic heterocyclic 6-membered ring containing one or two nitrogen atoms; R1=one or more substituents of the Ar nucleus, preferably in para position, and selected out of the group consisting of H, CH3, CH2-CH-(CH3)2, O-CH3, Cl, F, Br, CF3, NH2, S-CH3, CN, NO2 R2=H, CH3, C2H5, CH(CH3)2; R3= <IMAGE> Where R4=H, CH3, C2H5 R5=H, CH3 X=none O, S, NH, NCH3, -CH=CH-, -C=C-Y=O, NH, both in the racemic Form and in the isomeric enantiomeric forms, which produce a nootropic effect, i.e. memory enhancement and learning facilitation, as well as an analgesic effect.
申请公布号 AU4564593(A) 申请公布日期 1994.01.31
申请号 AU19930045645 申请日期 1993.07.06
申请人 FIDIA S.P.A. 发明人 ALESSANDRO BARTOLINI;CARLA GHELARDINI;ALBERTO GIOTTI;FULVIO GUALTIERI;SERENA SCAPECCHI;GINO TOFFANO
分类号 A61K31/46;A61P25/02;C07D451/04;C07D451/10 主分类号 A61K31/46
代理机构 代理人
主权项
地址