| 摘要 |
<p>Methods and compositions for in situ formation of protective films on body tissues. The compositions include hydroxypropyl cellulose and a weak carboxylic acid in a non-toxic volatile polar solvent, e.g., ethyl alcohol. The preferred carboxylic acids are salicylic acid, tannic acid, and mixtures thereof. A cross-linking agent, e.g., boric acid, incorporated in these compositions improves the physical properties of the film. Methods for in situ deposition of such films include the steps of drying the body tissue, applying the compositions and air drying the compositions to form the film in situ. The films also function as sustained-release matrices for topical medicines. The films themselves act as effective barriers to air, saliva and foods, and provide effective pain relief in the treatment of recurrent aphthous stomatitis.</p> |
