发明名称 |
PHARMACEUTICAL COMPOSITION CONTAINING PENTAMIDINE |
摘要 |
Pharmaceutical Compositions An aqueous solution containing, as active ingredient, pentamidine or a pharmaceutically acceptable salt thereof, and having a pH of less than 4.5 is more stable than conventional solutions of pentamidine. The pH of the solution is preferably less than 4.0, more preferably less than 3.5, and especially less than 3.0. The active ingredient is preferably pentamidine isethionate and the pH of the solution is preferably adjusted by the incorporation of hydrochloric acid. The solutions may be administered directly to the lung by nebulisation and are useful in the treatment of pneumo-cystic carinii pneumonia. |
申请公布号 |
CA1326453(C) |
申请公布日期 |
1994.01.25 |
申请号 |
CA19890597544 |
申请日期 |
1989.04.24 |
申请人 |
ANAEBONAM, ALOYSIUS |
发明人 |
ANAEBONAM, ALOYSIUS;DEVLIN, THERESA;CLEMENTE, EMMETT;RINDGEN, DIANE |
分类号 |
A61K9/00;A61K9/08;A61K31/155;A61K47/04;A61P33/02;C07C257/18 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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