| 摘要 |
Chemotherapy agents of interest are tested in untreated tumor cells and in tumor cells pretreated with buthionine sulfoximine (BSO) which reverses resistance related to elevated glutathione levels, and calcium channel blockers such as Verapamil which reduce resistance related to p-glycoprotein levels. The results of the tests are then integrated to provide a predictor of tumor drug sensitivity and the potential utility of pretreatment regimens. |
