PROCESS FOR PREPARATION OF PYRIDINE DERIVATIVES

摘要

The method for preparing pyridine derivs. of formula (I) comprises reacting an aromatic cpd. of formula (II) with substd. pyridine of formula (III) in an organic solvent in the presence of an alkali metal base such as NaOH or KOH. In the formulas, Ar=C5-10 aromatic hydrocarbon; Py= pyridine; X=H or lower alkyl; Y= halogen; R=nitrile, carboxylic amide or ester or carboxylic acid. Pref. the aromatic cpd. is phenyl acetonitrile or methylphenyl acetate; the substd. pyridine is 2-chloropyridine or 2- bromopyridine.