Stable porfimer sodium compositions and methods for their manufacture,申请号US19920873860-传众专利搜索

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发明名称	Stable porfimer sodium compositions and methods for their manufacture
摘要	A storage stable porfimer sodium (polyhematoporphyrin ether/ester) composition useful in the photodynamic therapy of cancer and other conditions is provided. The composition is characterized in that the percentage of ester linked porphyrin oligomers is less than 10% of the composition. Improved processes for preparing such compositions are also provided wherein acetylated hematoporphyrin is treated with alkali for sufficient time and temperature to reduce the amount of porphyrin oligomers joined by ester linkages to less than 10% of the composition.
申请公布号	US5244914(A)	申请公布日期	1993.09.14
申请号	US19920873860	申请日期	1992.04.27
申请人	AMERICAN CYANAMID COMPANY	发明人	CLAUSS, STEVEN L.;PASTEL, MICHAEL J.;ZAWADZKI, RAINER K.
分类号	A61K31/00;A61K31/40;A61K41/00;A61K51/00;A61P35/00;C07D487/22	主分类号	A61K31/00
代理机构		代理人
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