发明名称 Radiofrequency plasma biocompatibility treatment of inside surfaces of medical tubing and the like
摘要 Internal polymeric surfaces of medical devices are provided that have enhanced biocompatibility properties. The internal polymeric surface presents an anti-thrombogenic, fibrinolytic or thrombolytic interface with body fluids such as blood flowing through medical device tubing during implantation for medical procedures. The biocompatibility enhancing agent is secured to the polymeric substrate by a spacer molecule which is covalently bound to the internal polymeric surface which had been subjected to radiofrequency plasma treatment with a low pressure plasma medium of water vapor, oxygen or combination of water vapor and oxygen gas.
申请公布号 US5244654(A) 申请公布日期 1993.09.14
申请号 US19910720410 申请日期 1991.06.25
申请人 CORDIS CORPORATION 发明人 NARAYANAN, PALLASSANA V.
分类号 A61K35/62;A61L33/00;A61L33/08;A61L33/10;B05D3/06;B05D7/24;B29C59/14;C08J7/04;C08J7/12 主分类号 A61K35/62
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