发明名称 |
Design, cloning and expression of humanized monoclonal antibodies against human interleukin-5 |
摘要 |
A monoclonal antibody is provided which specifically binds to human interleukin-5. Also provided are a hybridoma which produces the monoclonal antibody; complementary DNAs which encode the heavy and light chain variable regions of the monoclonal antibody and CDRs therefrom; humanized monoclonal antibodies; and pharmaceutical compositions comprising the monoclonal antibody or anti-idiotypic antibodies directed against it, humanized monoclonal antibodies, binding fragments, binding compositions or single-chain binding proteins derived from the antibody and a physiologically acceptable carrier. |
申请公布号 |
AU3656093(A) |
申请公布日期 |
1993.09.03 |
申请号 |
AU19930036560 |
申请日期 |
1993.02.04 |
申请人 |
SCHERING CORPORATION |
发明人 |
CHUAN-CHU CHOU;NICHOLAS J MURGOLO;JOHN S. ABRAMS;CHUNG-HER JENH;MARY E PETRO;JON E SILVER;STEPHEN TINDALL;WILLIAM T WINDSOR;PAUL J ZAVODNY |
分类号 |
C12N15/02;A61K38/00;A61K39/395;A61P37/00;C07K16/24;C07K16/46;C12N5/10;C12N15/09;C12N15/13;C12P21/08;C12R1/91 |
主分类号 |
C12N15/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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