| 摘要 |
A compound of the formula: <IMAGE> in which R1 is hydrogen, alkyl or phenylalkyl; R2 is hydrogen, alkyl, alkenyl or phenylalkyl; or R1 and R2 taken together are -CH2CH2-, -CH2C(R6)(R7)CH2- or -CH2C(R8)(R9)-C(R10)(R11)CH2-, where R6, R8 and R10 are, independently, hydrogen, alkyl of 1 to 6 carbon atoms or hydroxyl and R7, R9 and R11 are, independently, hydrogen or alkyl of 1 to 6 carbon atoms; A is alkylene or alkenylene; X is CO2R3 in which R3 is hydrogen or alkyl, P(O)(OR4)(OR5) in which R4 and R5 are, independently, hydrogen or alkyl, 3,5-dioxo-1,2,4-oxadiazolidin-2-yl or 5-tetrazolyl; or a pharmaceutically acceptable salt thereof are useful as neuroprotectants.
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